Agnes Bruckner began acting on television in the late 1990s and has since appeared in seven films, including The Woods, Blue Car, and Murder By Numbers. Bruckner got her first lead role in the independent film Blue Car (2002). Bruckner received an Independent Spirit Award nomination for "Best Female Lead" for the role. Bruckner has appeared in episodes of the television series 24 and Alias. Bruckner appeared in film Blood and Chocolate (2008), Kill Theory (2008), Vacancy 2: The First Cut (2009) and The Craigslist Killer (2011).